ST14 antibody (Internal Region)
Quick Overview for ST14 antibody (Internal Region) (ABIN6263143)
Target
See all ST14 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Internal Region
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Specificity
- Matriptase Antibody detects endogenous levels of total Matriptase.
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Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human Matriptase, corresponding to a region within the internal amino acids.
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Isotype
- IgG
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Application Notes
- WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
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Expiry Date
- 12 months
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- ST14 (Suppression of Tumorigenicity 14 (ST14))
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Alternative Name
- ST14
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Background
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Description: Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing.
Gene: ST14
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Molecular Weight
- 95kDa
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Gene ID
- 6768
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UniProt
- Q9Y5Y6
Target
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