MEMO1 antibody (N-Term)

Catalog No. ABIN6263219

This Rabbit Polyclonal antibody specifically detects MEMO1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for MEMO1 antibody (N-Term) (ABIN6263219)

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEMO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MEMO1 Antibody

Binding Specificity: N-Term

Specificity: MEMO1 Antibody detects endogenous levels of total MEMO1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MEMO1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MEMO1

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Alternative Name: MEMO1

Background:

Description: May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.

Gene: MEMO1

Molecular Weight: 33 kDa

Gene ID: 51072

UniProt: Q9Y316