MYO3B antibody (C-Term)

Catalog No. ABIN6263481

The Rabbit Polyclonal anti-MYO3B antibody has been validated for WB, ELISA and IHC. It is suitable to detect MYO3B in samples from Human.

Quick Overview for MYO3B antibody (C-Term) (ABIN6263481)

Target: MYO3B (Myosin IIIB (MYO3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO3B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MYO3B Antibody

Binding Specificity: C-Term

Specificity: MYO3B Antibody detects endogenous levels of total MYO3B.

Predicted Reactivity: Pig,Zebrafish,Horse

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MYO3B, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MYO3B

Target: MYO3B (Myosin IIIB (MYO3B))

Alternative Name: MYO3B

Background:

Description: Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments.

Gene: MYO3B

Molecular Weight: 152 kDa

Gene ID: 140469

UniProt: Q8WXR4