NDUFA13 antibody (N-Term)

Catalog No. ABIN6263558

This Rabbit Polyclonal antibody specifically detects NDUFA13 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NDUFA13 antibody (N-Term) (ABIN6263558)

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFA13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NDUFA13 Antibody

Binding Specificity: N-Term

Specificity: NDUFA13 Antibody detects endogenous levels of total NDUFA13.

Predicted Reactivity: Pig,Zebrafish,Bovine,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NDUFA13, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NDUFA13

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Alternative Name: NDUFA13

Background:

Description: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis (PubMed:27626371). Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:27626371). Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes (PubMed:15753091).

Gene: NDUFA13

Molecular Weight: 17kDa

Gene ID: 51079

UniProt: Q9P0J0

Pathways: Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling