NKRF antibody (N-Term)

Catalog No. ABIN6263644

This anti-NKRF antibody is a Rabbit Polyclonal antibody detecting NKRF in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for NKRF antibody (N-Term) (ABIN6263644)

Target: NKRF (NFKB Repressing Factor (NKRF))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKRF antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NKRF Antibody

Binding Specificity: N-Term

Specificity: NKRF Antibody detects endogenous levels of total NKRF.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NKRF, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NKRF

Target: NKRF (NFKB Repressing Factor (NKRF))

Alternative Name: NKRF

Background:

Description: Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.

Gene: NKRF

Molecular Weight: 79 kDa

Gene ID: 55922

UniProt: O15226