NOG antibody (Internal Region)

Catalog No. ABIN6263681

This Rabbit Polyclonal antibody specifically detects NOG in WB, ELISA, ICC and IF. It exhibits reactivity toward Human and Rat.

Quick Overview for NOG antibody (Internal Region) (ABIN6263681)

Target: NOG (Noggin (NOG))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-NOG Antibody

Binding Specificity: Internal Region

Specificity: NOG Antibody detects endogenous levels of total NOG.

Predicted Reactivity: Bovine,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NOG, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NOG

Target: NOG (Noggin (NOG))

Alternative Name: NOG

Background:

Description: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (PubMed:21976273, PubMed:26643732).

Gene: NOG

Molecular Weight: 26 kDa

Gene ID: 9241

UniProt: Q13253

Pathways: Stem Cell Maintenance, Tube Formation