OCA2 antibody (N-Term)

Catalog No. ABIN6263792

This Rabbit Polyclonal antibody specifically detects OCA2 in WB, ELISA, IHC, ICC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for OCA2 antibody (N-Term) (ABIN6263792)

Target: OCA2 (P Protein (OCA2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OCA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-OCA2 Antibody

Binding Specificity: N-Term

Specificity: OCA2 Antibody detects endogenous levels of total OCA2.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human OCA2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for OCA2

Target: OCA2 (P Protein (OCA2))

Alternative Name: OCA2

Target Type: Viral Protein

Background:

Description: Could be involved in the transport of tyrosine, the precursor to melanin synthesis, within the melanocyte. Regulates the  pH of melanosome and the melanosome maturation. One of the components of the mammalian pigmentary system. Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis. May serve as a key control point at which ethnic skin color variation is determined. Major determinant of brown and/or blue eye color.

Gene: OCA2

Molecular Weight: 92kDa

Gene ID: 4948

UniProt: Q04671