CDKN2B antibody (Internal Region)
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- Target See all CDKN2B Antibodies
- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDKN2B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- P15 INK4b Antibody detects endogenous levels of total p15 INK4b.
- Predicted Reactivity
- Bovine,Horse,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human p15 INK4b, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product CDKN2B Primary Antibody
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- Application Notes
- WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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ANRIL inhibits p15(INK4b) through the TGFβ1 signaling pathway in human esophageal squamous cell carcinoma." in: Cellular immunology, Vol. 289, Issue 1-2, pp. 91-6, (2014) (PubMed).
: "
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ANRIL inhibits p15(INK4b) through the TGFβ1 signaling pathway in human esophageal squamous cell carcinoma." in: Cellular immunology, Vol. 289, Issue 1-2, pp. 91-6, (2014) (PubMed).
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- Target
- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
- Alternative Name
- CDKN2B (CDKN2B Products)
- Background
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Description: Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.
Gene: CDKN2B
- Molecular Weight
- 14kDa
- Gene ID
- 1030
- UniProt
- P42772
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases
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