CDKN2B antibody

Catalog No. ABIN7182212

Product Details anti-CDKN2B Antibody

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKN2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Human p15 INK antibody.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CDKN2B

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Alternative Name: CDKN2B (CDKN2B Products)

Synonyms: p14-INK4b antibody, cdk4l antibody, ink4b antibody, mts2 antibody, p15 antibody, p15ink4b antibody, tp15 antibody, CDK4I antibody, INK4B antibody, MTS2 antibody, P15 antibody, TP15 antibody, p15INK4b antibody, AV083695 antibody, INK4b antibody, p15(INK4b) antibody, CDKN2A antibody, cyclin dependent kinase inhibitor 2B antibody, Cyclin-dependent kinase 4 inhibitor B antibody, cyclin-dependent kinase inhibitor 2B antibody, cyclin-dependent kinase inhibitor 2B L homeolog antibody, cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) antibody, CDKN2B antibody, cdn2b antibody, cdkn2b antibody, cdkn2b.L antibody, Cdkn2b antibody

Background:

Background: Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.

Nynke Y. Rots, Blood, Apr 1999, 93: 2721 - 2729.
Stefan Faderl, Clin. Cancer Res., Jul 1999, 5: 1855.
George Wu, Mol. Biol. Cell, Mar 2007, 18: 1018 - 1029.
A. Koenig, Vet. Pathol., Jul 2002, 39: 458.

Aliases: CDK inhibitory protein antibody, CDK4B Inhibitor antibody, Cdkn2b antibody, CDN2B_HUMAN antibody, Cyclin dependent kinase 4 inhibitor B antibody, Cyclin Dependent Kinase Inhibitor 2B antibody, Cyclin dependent kinase inhibitor 2B p15 inhibits CDK4 antibody, Cyclin dependent kinases 4 and 6 binding protein antibody, Cyclin-dependent kinase 4 inhibitor B antibody, INK4B antibody, MTS 2 antibody, MTS-2 antibody, MTS2 antibody, Multiple tumor suppressor 2 antibody, Multiple Tumor Supressor 2 antibody, OTTHUMP00000021154 antibody, OTTHUMP00000021155 antibody, p14 CDK inhibitor antibody, p14 INK4b antibody, p14-INK4b antibody, P15 antibody, p15 CDK inhibitor antibody, p15 inhibits CDK4 antibody, p15 INK4b antibody, p15-INK4b antibody, p15INK4B antibody, TP 15 antibody, TP15 antibody

UniProt: P42772

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases