PAOX antibody (Internal Region)
Quick Overview for PAOX antibody (Internal Region) (ABIN6264032)
Target
See all PAOX AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Internal Region
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Specificity
- PAOX Antibody detects endogenous levels of total PAOX.
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Predicted Reactivity
- Bovine,Horse,Sheep,Rabbit
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human PAOX, corresponding to a region within the internal amino acids.
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Isotype
- IgG
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Application Notes
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
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Expiry Date
- 12 months
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- PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))
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Alternative Name
- PAOX
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Background
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Description: Flavoenzyme which catalyzes the oxidation of N1-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N1-acetylspermidine to putrescine. Substrate specificity: N1-acetylspermine = N1-acetylspermidine > N1,N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Gene: PAOX
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Molecular Weight
- 70 kDa
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Gene ID
- 196743
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UniProt
- Q6QHF9
Target
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