PHOX2B antibody (Internal Region)

Catalog No. ABIN6264185

This Rabbit Polyclonal antibody specifically detects PHOX2B in WB, ELISA, IF and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for PHOX2B antibody (Internal Region) (ABIN6264185)

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-PHOX2B Antibody

Binding Specificity: Internal Region

Specificity: PHOX2B Antibody detects endogenous levels of total PHOX2B.

Predicted Reactivity: Pig,Bovine,Horse,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PHOX2B, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: PHOX2B

Background:

Description: Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.

Gene: PHOX2B

Molecular Weight: 32 kDa

Gene ID: 8929

UniProt: Q99453