PRKCDBP antibody (Internal Region)

Catalog No. ABIN6264426

The Rabbit Polyclonal anti-PRKCDBP antibody has been validated for WB, IHC, IF and ICC. It is suitable to detect PRKCDBP in samples from Human, Mouse and Rat.

Quick Overview for PRKCDBP antibody (Internal Region) (ABIN6264426)

Target: PRKCDBP (Protein Kinase C, delta Binding Protein (PRKCDBP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKCDBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-PRKCDBP Antibody

Binding Specificity: Internal Region

Specificity: PRKCDBP Antibody detects endogenous levels of total PRKCDBP.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PRKCDBP, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PRKCDBP

Target: PRKCDBP (Protein Kinase C, delta Binding Protein (PRKCDBP))

Alternative Name: CAVIN3

Background:

Description: Regulates the traffic and/or budding of caveolae (PubMed:19262564). Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (By similarity).

Gene: CAVIN3

Molecular Weight: 35-40 kDa

Gene ID: 112464

UniProt: Q969G5