REV3L antibody (N-Term)

Catalog No. ABIN6264707

This Rabbit Polyclonal antibody specifically detects REV3L in ELISA, IHC and WB. It exhibits reactivity toward Mouse and Human.

Quick Overview for REV3L antibody (N-Term) (ABIN6264707)

Target: REV3L (REV3-Like, Polymerase (DNA Directed), Zeta, Catalytic Subunit (REV3L))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REV3L antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-REV3L Antibody

Binding Specificity: N-Term

Specificity: REV3L Antibody detects endogenous levels of total REV3L.

Predicted Reactivity: Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human REV3L, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for REV3L

Target: REV3L (REV3-Like, Polymerase (DNA Directed), Zeta, Catalytic Subunit (REV3L))

Alternative Name: REV3L

Background:

Description: Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function.

Gene: REV3L

Molecular Weight: 352kDa

Gene ID: 5980

UniProt: O60673

Pathways: DNA Damage Repair