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Sp3/4 antibody

This Rabbit Polyclonal antibody specifically detects Sp3/4 in WB, ELISA, IF, IHC and ICC. It exhibits reactivity toward Human.
Catalog No. ABIN6265247

Quick Overview for Sp3/4 antibody (ABIN6265247)

Target

Sp3/4

Reactivity

  • 14
  • 13
  • 11
  • 2
  • 2
Human

Host

  • 14
Rabbit

Clonality

  • 14
Polyclonal

Conjugate

  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Sp3/4 antibody is un-conjugated

Application

  • 7
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • Specificity

    Sp3/4 Antibody detects endogenous levels of total Sp3/4

    Cross-Reactivity

    Human

    Purification

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human Sp3/4

    Isotype

    IgG
  • Application Notes

    WB 1:1000 IHC 1:200, IF/ICC 1:100-1:500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C.Stable for 12 months from date of receipt

    Expiry Date

    12 months
  • Target

    Sp3/4

    Background

    Description: Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping.

    Gene: SP3

    Molecular Weight

    82kDa

    Gene ID

    6670

    UniProt

    Q02447, Q02446
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