TAS2R43 antibody

Catalog No. ABIN6265463

Product Details anti-TAS2R43 Antibody

Target: TAS2R43 (Taste Receptor, Type 2, Member 43 (TAS2R43))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAS2R43 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: TAS2R43 Antibody detects endogenous levels of total TAS2R43

Cross-Reactivity: Human

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TAS2R43

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for TAS2R43

Target: TAS2R43 (Taste Receptor, Type 2, Member 43 (TAS2R43))

Alternative Name: TAS2R43 (TAS2R43 Products)

Background:

Description: Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).

Gene: TAS2R43

Molecular Weight: 35 kDa

Gene ID: 259289

UniProt: P59537