GTF3C4 antibody (Internal Region)

Catalog No. ABIN6265529

This Rabbit Polyclonal antibody specifically detects GTF3C4 in WB, ELISA, IF and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for GTF3C4 antibody (Internal Region) (ABIN6265529)

Target: GTF3C4 (General Transcription Factor IIIC, Polypeptide 4 (GTF3C4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF3C4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-GTF3C4 Antibody

Binding Specificity: Internal Region

Specificity: TF3C4 Antibody detects endogenous levels of total TF3C4.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TF3C4, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GTF3C4

Target: GTF3C4 (General Transcription Factor IIIC, Polypeptide 4 (GTF3C4))

Alternative Name: GTF3C4

Background:

Description: Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.

Gene: GTF3C4

Molecular Weight: 92 kDa

Gene ID: 9329

UniProt: Q9UKN8