TIMM22 antibody (Internal Region)

Catalog No. ABIN6265572

The Rabbit Polyclonal anti-TIMM22 antibody is suitable to detect TIMM22 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ICC and IF.

Quick Overview for TIMM22 antibody (Internal Region) (ABIN6265572)

Target: TIMM22 (Translocase of Inner Mitochondrial Membrane 22 Homolog (TIMM22))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM22 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-TIMM22 Antibody

Binding Specificity: Internal Region

Specificity: TIM22 Antibody detects endogenous levels of total TIM22.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TIM22, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TIMM22

Target: TIMM22 (Translocase of Inner Mitochondrial Membrane 22 Homolog (TIMM22))

Alternative Name: TIMM22

Background:

Description: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).

Gene: TIMM22

Molecular Weight: 20 kDa

Gene ID: 29928

UniProt: Q9Y584