USP18 antibody (N-Term)

Catalog No. ABIN6265914

The Rabbit Polyclonal anti-USP18 antibody has been validated for WB and ELISA. It is suitable to detect USP18 in samples from Human.

Quick Overview for USP18 antibody (N-Term) (ABIN6265914)

Target: USP18 (Ubiquitin Specific Peptidase 18 (USP18))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP18 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-USP18 Antibody

Binding Specificity: N-Term

Specificity: USP18 Antibody detects endogenous levels of total USP18.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human USP18, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for USP18

Target: USP18 (Ubiquitin Specific Peptidase 18 (USP18))

Alternative Name: USP18

Background:

Description: Involved in the regulation of inflammatory response to interferon type 1 (PubMed:27325888). Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.

Gene: USP18

Molecular Weight: 43 kDa.

Gene ID: 11274

UniProt: Q9UMW8