ZFYVE9 antibody (C-Term)

Catalog No. ABIN6266103

The Rabbit Polyclonal anti-ZFYVE9 antibody is suitable to detect ZFYVE9 in samples from Human and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for ZFYVE9 antibody (C-Term) (ABIN6266103)

Target: ZFYVE9 (Zinc Finger, FYVE Domain Containing 9 (ZFYVE9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFYVE9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ZFYVE9 Antibody

Binding Specificity: C-Term

Specificity: ZFYVE9 Antibody detects endogenous levels of total ZFYVE9.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZFYVE9, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ZFYVE9

Target: ZFYVE9 (Zinc Finger, FYVE Domain Containing 9 (ZFYVE9))

Alternative Name: ZFYVE9

Background:

Description: Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.

Gene: ZFYVE9

Molecular Weight: 156 kDa

Gene ID: 9372

UniProt: O95405

Pathways: Protein targeting to Nucleus