CXCR3 antibody (Internal Region)

Catalog No. ABIN6266198

This Rabbit Polyclonal antibody specifically detects CXCR3 in WB, ELISA, IHC, ICC and IF. It exhibits reactivity toward Human, Mouse and Ratand has been mentioned in 1 publication.

Quick Overview for CXCR3 antibody (Internal Region) (ABIN6266198)

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-CXCR3 Antibody

Binding Specificity: Internal Region

Specificity: CXCR3 Antibody detects endogenous levels of total CXCR3.

Predicted Reactivity: Pig,Horse

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CXCR3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB(1:500-1:2000), IHC(1:50-1:100), IF/ICC(1:100-1:500), ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

References for anti-CXCR3 antibody (ABIN6266198)

Yin, Song, Yang, Zheng, Liu, Shen: "Effect of CXCR3/HO-1 genes modified bone marrow mesenchymal stem cells on small bowel transplant rejection." in: World journal of gastroenterology, Vol. 23, Issue 22, pp. 4016-4038, (2018) (PubMed).

Target Details for CXCR3

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Alternative Name: CXCR3

Background:

Description: Isoform 1: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed:12782716). Binds to CCL21. Probably promotes cell chemotaxis response.

Gene: CXCR3

Molecular Weight: 46kDa

Gene ID: 2833

UniProt: P49682