PIBF1 antibody (C-Term)

Catalog No. ABIN6266307

The Rabbit Polyclonal anti-PIBF1 antibody is suitable to detect PIBF1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA, IF and ICC.

Quick Overview for PIBF1 antibody (C-Term) (ABIN6266307)

Target: PIBF1 (Progesterone Immunomodulatory Binding Factor 1 (PIBF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIBF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-PIBF1 Antibody

Binding Specificity: C-Term

Specificity: PIBF1 Antibody detects endogenous levels of total PIBF1.

Predicted Reactivity: Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PIBF1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC 1:50-1:100, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PIBF1

Target: PIBF1 (Progesterone Immunomodulatory Binding Factor 1 (PIBF1))

Alternative Name: PIBF1

Background:

Description: Isoform 1: Pericentriolar protein required to maintain mitotic spindle pole integrity (PubMed:21224392). Required for the centrosomal accumulation of PCM1 and the recruitment of centriolar satellite proteins such as BBS4. Via association with PCM1 may be involved in primary cilia formation (PubMed:23110211). Required for CEP63 centrosomal localization and its interaction with WDR62. Together with CEP63 promotes centriole duplication. Promotes the centrosomal localization of CDK2 (PubMed:26297806).

Gene: PIBF1

Molecular Weight: 90kDa

Gene ID: 10464

UniProt: Q8WXW3