Lamin B antibody

Catalog No. ABIN6268707

The Rabbit Polyclonal anti-Lamin B antibody has been validated for WB, IHC, ICC, ELISA and IF. It is suitable to detect Lamin B in samples from Human, Rat, Mouse, Fish and Monkey. There are 2+ publications available.

Quick Overview for Lamin B antibody (ABIN6268707)

Target: Lamin B

Reactivity: Human, Rat, Mouse, Fish, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)

Product Details anti-Lamin B Antibody

Specificity: Lamin B Antibody detects endogenous levels of total Lamin B

Cross-Reactivity: Fish, Human, Monkey, Mouse (Murine), Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Lamin B

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

References for anti-Lamin B antibody (ABIN6268707)

Zheng, Feng, Jiang, Wu, Tang, Kuang, Zeng, Zhou, Liu: "Selenium deficiency impaired immune function of the immune organs in young grass carp (Ctenopharyngodon idella)." in: Fish & shellfish immunology, Vol. 77, pp. 53-70, (2018) (PubMed).

Yu, Bai, Liu, Yang, Yuan, Zou, Qu, Tian, Song, Zhang, Li, Liu, Wang, Ren, Li: "Fibroblast growth factor (FGF21) protects mouse liver against D-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways." in: Molecular and cellular biochemistry, Vol. 403, Issue 1-2, pp. 287-99, (2015) (PubMed).

Target Details for Lamin B

Target: Lamin B

Background:

Description: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.

Gene: LMNB1

Molecular Weight: 66 kDa

Gene ID: 4001

UniProt: P20700