SETD2 antibody

Catalog No. ABIN6290482

This Rabbit Polyclonal antibody specifically detects SETD2 in WB. It exhibits reactivity toward Mouse and Rat.

Quick Overview for SETD2 antibody (ABIN6290482)

Target: SETD2 (SET Domain Containing 2 (SETD2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETD2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SETD2 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human SETD2

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:500

Comment:

Ubiquitously expressed

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for SETD2

Target: SETD2 (SET Domain Containing 2 (SETD2))

Alternative Name: SETD2

Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Molecular Weight: 287.597 kDa

Gene ID: 29072

UniProt: Q9BYW2

Pathways: Tube Formation