HIC1 antibody

Catalog No. ABIN6290500

This Rabbit Polyclonal antibody specifically detects HIC1 in WB. It exhibits reactivity toward Human and Rat.

Quick Overview for HIC1 antibody (ABIN6290500)

Target: HIC1 (Hypermethylated in Cancer 1 (HIC1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIC1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human HIC1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Ubiquitously expressed with highest levels found in lung, colon, prostate, thymus, testis and ovary, Expression is absent or decreased in many tumor cells

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for HIC1

Target: HIC1 (Hypermethylated in Cancer 1 (HIC1))

Alternative Name: HIC1

Background: This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight: 76.508 kDa

Gene ID: 3090

UniProt: Q14526

Pathways: Positive Regulation of Response to DNA Damage Stimulus