RNF4 antibody
Quick Overview for RNF4 antibody (ABIN6291207)
Target
See all RNF4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of human RNF4
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Isotype
- IgG
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Application Notes
- WB 1:500 - 1:1000
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Comment
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Widely expressed at low levels in many tissues
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- RNF4 (Ring Finger Protein 4 (RNF4))
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Alternative Name
- RNF4
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Background
- The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.
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Molecular Weight
- 21.319 kDa
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Gene ID
- 6047
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UniProt
- P78317
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
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