RNF4 antibody (C-Term)

Catalog No. ABIN954575

The Rabbit Polyclonal anti-RNF4 antibody is suitable to detect RNF4 in samples from Human. It has been validated for WB and EIA.

Quick Overview for RNF4 antibody (C-Term) (ABIN954575)

Target: RNF4 (Ring Finger Protein 4 (RNF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-RNF4 Antibody

Binding Specificity: AA 94-123, C-Term

Specificity: This antibody recognizes Human RNF4. Other species not tested.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 94-123 amino acids from the C-terminal region of human RNF4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RNF4

Target: RNF4 (Ring Finger Protein 4 (RNF4))

Alternative Name: RNF4

Background: The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.Synonyms: E3 ubiquitin ligase RNF4, RES4-26, Ring finger protein 4, SNURF

Molecular Weight: 21319 Da

Gene ID: 6047

NCBI Accession: NP_001171938

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway