CD235b/GYPB antibody

Catalog No. ABIN6293128

This Rabbit Polyclonal antibody specifically detects CD235b/GYPB in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for CD235b/GYPB antibody (ABIN6293128)

Target: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD235b/GYPB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD235b/GYPB Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human GYPB

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for CD235b/GYPB

Target: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Alternative Name: GYPB

Background: Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97 % sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.

Molecular Weight: 9.782 kDa

Gene ID: 2994

UniProt: P06028