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CD235b/GYPB antibody (AA 21-91) (Biotin)

GYPB Reactivity: Human ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1388329
  • Target See all CD235b/GYPB (GYPB) Antibodies
    CD235b/GYPB (GYPB) (Glycophorin B (GYPB))
    Binding Specificity
    • 14
    • 7
    • 1
    AA 21-91
    Reactivity
    • 24
    • 1
    Human
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD235b/GYPB antibody is conjugated to Biotin
    Application
    • 13
    • 13
    • 9
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Glycophorin B
    Isotype
    IgG
    Top Product
    Discover our top product GYPB Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    CD235b/GYPB (GYPB) (Glycophorin B (GYPB))
    Alternative Name
    GYPB (GYPB Products)
    Synonyms
    CD235b antibody, GPB antibody, GPB.NY antibody, GYPHe.NY antibody, GpMiIII antibody, HGpMiIII antibody, HGpMiVI antibody, HGpMiX antibody, MNS antibody, PAS-3 antibody, SS antibody, glycophorin B (MNS blood group) antibody, GYPB antibody
    Background

    Synonyms: SS, GPB, MNS, PAS-3, CD235b, GPB.NY, HGpMiX, GpMiIII, HGpMiVI, GYPHe.NY, HGpMiIII, Glycophorin-B, SS-active sialoglycoprotein, Sialoglycoprotein delta, GYPB

    Background: Glycophorins A, B and C are sialoglycoproteins of the human erythrocyte membrane, which bear the antigenic determinants for the MN, Ss and Gerbich blood groups, respectively. Glycophorins span the membrane once and present their amino-terminal end to the extracellular surface of the human erythrocyte. The genetic array of expressed glycophorin surface antigens on erythrocytes defines the blood group phenotype of the individual. The human Glycophorin A gene maps to chromosome 4q31.21, contains seven exons which are 97 % homologous to Glycophorin B, and encodes a 150 amino acid protein. The human Glycophorin B gene maps to chromosome 4q31.21 and encodes a 91 amino acid protein. The human Glycophorin C gene maps to chromosome 2q14.3 and contains four exons. Glycophorin C transcript can generate two protein isoforms. Isoform 1 includes all 4 exons and encodes the full length 128 amino acid protein. Isoform 2 is missing exon 2 and encodes a 109 amino acid protein, which specifies the Yus subtype of the Gerbich phenotype.

    Gene ID
    2994
    UniProt
    P06028
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