CHRND antibody
Quick Overview for CHRND antibody (ABIN6293997)
Target
See all CHRND AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of human CHRND
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Isotype
- IgG
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Application Notes
- WB 1:500 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))
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Alternative Name
- CHRND
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Background
- The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 58.895 kDa
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Gene ID
- 1144
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UniProt
- Q07001
Target
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