CHRND antibody (AA 22-245)

Catalog No. ABIN6138596

Product Details anti-CHRND Antibody

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Binding Specificity: AA 22-245

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRND antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LNEEERLIRH LFQEKGYNKE LRPVAHKEES VDVALALTLS NLISLKEVEE TLTTNVWIEH GWTDNRLKWN AEEFGNISVL RLPPDMVWLP EIVLENNNDG SFQISYSCNV LVYHYGFVYW LPPAIFRSSC PISVTYFPFD WQNCSLKFSS LKYTAKEITL SLKQDAKENR TYPVEWIIID PEGFTENGEW EIVHRPARVN VDPRAPLDSP SRQDITFYLI IRRK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-245 of human CHRND (NP_000742.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHRND

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Alternative Name: CHRND (CHRND Products)

Synonyms: ACHRD antibody, CMS2A antibody, FCCMS antibody, SCCMS antibody, wu:fa01e01 antibody, zgc:110469 antibody, CHNRD antibody, MGC97613 antibody, Achr-4 antibody, Acrd antibody, L10076 antibody, chnrd antibody, chrng antibody, cholinergic receptor nicotinic delta subunit antibody, cholinergic receptor, nicotinic, delta (muscle) antibody, cholinergic receptor, nicotinic, delta antibody, cholinergic receptor nicotinic gamma subunit antibody, cholinergic receptor, nicotinic delta antibody, cholinergic receptor, nicotinic, delta polypeptide antibody, cholinergic receptor, nicotinic delta L homeolog antibody, CHRND antibody, chrnd antibody, CHRNG antibody, Chrnd antibody, chrnd.L antibody

Background: The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.,CHRND,ACHRD,CMS2A,CMS3A,CMS3B,CMS3C,FCCMS,SCCMS,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRND

Molecular Weight: 57 kDa/58 kDa

Gene ID: 1144

UniProt: Q07001