Podoplanin antibody (AA 24-126)

Catalog No. ABIN6294416

The Mouse Monoclonal anti-Podoplanin antibody is suitable to detect Podoplanin in samples from Human. It has been validated for WB, IHC, FACS and IF.

Quick Overview for Podoplanin antibody (AA 24-126) (ABIN6294416)

Target: Podoplanin (PDPN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Podoplanin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-Podoplanin Antibody

Binding Specificity: AA 24-126

Purpose: Mouse anti-Human Podoplanin Antibody / gp36 [Sodium Azide Free]

Specificity: Cell surface, cytoplasmic

Purification: A human recombinant partial protein corresponding to amino acids 24-126 was used as the immunogen for the Podoplanin antibody.

Immunogen: A human recombinant partial protein corresponding to amino acids 24-126 was used as the immunogen for the Podoplanin antibody.

Application Details

Application Notes: WB: 0.5-1 μg/mL
IF: 0.5-1 μg/mL
FACS: 0.5-1 μg/million cells in 0.1ml
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Podoplanin

Target: Podoplanin (PDPN)

Alternative Name: Podoplanin

Background:

Target Description: Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

Gene Symbol: PDPN///GP36///PSEC0003///PSEC0025

Gene ID: 10630

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport