Uroplakin 3A antibody (AA 260-279)

Catalog No. ABIN6294436

This Rabbit Polyclonal antibody specifically detects Uroplakin 3A in WB, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for Uroplakin 3A antibody (AA 260-279) (ABIN6294436)

Target: Uroplakin 3A (UPK3A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 3A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-Uroplakin 3A Antibody

Binding Specificity: AA 260-279

Purpose: Rabbit anti-Human Uroplakin 3A Antibody [Sodium Azide Free]

Specificity: Cell surface

Purification: A synthetic peptide, aa 260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin 3A was used as the immunogen for this antibody.

Immunogen: A synthetic peptide, aa 260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin 3A was used as the immunogen for this antibody.

Application Details

Application Notes: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Uroplakin 3A

Target: Uroplakin 3A (UPK3A)

Alternative Name: Uroplakin-3a

Background:

Target Description: Uroplakin 3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. Uroplakin 3A may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. Uroplakin 3A has been shown as a helpful marker for the detection of bladder cancer.

Gene Symbol: UPK3A///UPK3

Gene ID: 7380

UniProt: O75631