Uroplakin 3A antibody (AA 260-279)

Catalog No. ABIN6940860

Product Details anti-Uroplakin 3A Antibody

Target: Uroplakin 3A (UPK3A)

Binding Specificity: AA 260-279

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 3A antibody is un-conjugated

Application: Western Blotting (WB)

Immunogen: A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

Isotype: IgG

Application Details

Application Notes:

Positive Control: HEK293 cells. Bladder carcinoma.

Known Application: Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Uroplakin 3A

Target: Uroplakin 3A (UPK3A)

Alternative Name: UPK3A (UPK3A Products)

Synonyms: UP3A antibody, UPIII antibody, UPIIIA antibody, UPK3 antibody, upk3 antibody, upiii antibody, MGC75921 antibody, 1110017C07Rik antibody, UP3a antibody, Upk3 antibody, up3a antibody, upiiia antibody, upk3a antibody, xUPIII antibody, uroplakin 3A antibody, uroplakin 3 antibody, uroplakin 3A L homeolog antibody, UPK3A antibody, upk3a antibody, Upk3a antibody, LOC100008738 antibody, upk3a.L antibody

Background: Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.

Gene ID: 7380

UniProt: O75631