ALDH1A1 antibody (AA 315-434)

Catalog No. ABIN6294471

This anti-ALDH1A1 antibody is a Mouse Monoclonal antibody detecting ALDH1A1 in WB, IHC, IF and FACS. Suitable for Human.

Quick Overview for ALDH1A1 antibody (AA 315-434) (ABIN6294471)

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ALDH1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-ALDH1A1 Antibody

Binding Specificity: AA 315-434

Purpose: Mouse anti-Human ALDH1 Antibody [Sodium Azide Free]

Specificity: Cytoplasmic

Purification: A human partial recombinant ALDH1A1 protein (AA 315-434) was used as the immunogen for this ALDH1 antibody.

Immunogen: A human partial recombinant ALDH1A1 protein (AA 315-434) was used as the immunogen for this ALDH1 antibody.

Application Details

Application Notes: FACS: 0.5-1 μg/10^6 cells
Western blot: 1-2 μg/mL
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Alternative Name: Retinal dehydrogenase 1

Background:

Target Description: ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.

Gene Symbol: ALDH1A1///ALDC///ALDH1///PUMB1

Gene ID: 216

UniProt: P00352

Pathways: Dopaminergic Neurogenesis