TIMP2 antibody (AA 56-66)

Catalog No. ABIN6294556

This Mouse Monoclonal antibody specifically detects TIMP2 in WB, IF and IHC (fp). It exhibits reactivity toward Human, Rat, Mouse, Cow, Zebrafish (Danio rerio), Rabbit and Guinea Pig.

Quick Overview for TIMP2 antibody (AA 56-66) (ABIN6294556)

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reactivity: Human, Rat, Mouse, Cow, Zebrafish (Danio rerio), Rabbit, Guinea Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This TIMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-TIMP2 Antibody

Binding Specificity: AA 56-66

Purpose: Mouse anti-Human/Mouse/Rat/Guinea pig/Rabbit/Cow/Zebrafish TIMP2 Antibody [Sodium Azide Free]

Specificity: Cytoplasmic, cell surface, secreted

Purification: Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this TIMP-2 antibody.

Immunogen: Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this TIMP-2 antibody.

Application Details

Application Notes: IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
WB: 0.5-1 μg/mL
IF: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Alternative Name: Metalloproteinase inhibitor 2

Background:

Target Description: It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Gene Symbol: TIMP2

Gene ID: 7077

UniProt: P16035

Pathways: cAMP Metabolic Process