Thrombomodulin antibody (AA 69-194)

Catalog No. ABIN6294573

This anti-Thrombomodulin antibody is a Mouse Monoclonal antibody detecting Thrombomodulin in IHC, ELISA, FACS, IF and Coat. Suitable for Human.

Quick Overview for Thrombomodulin antibody (AA 69-194) (ABIN6294573)

Target: Thrombomodulin (THBD)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Thrombomodulin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)

Product Details anti-Thrombomodulin Antibody

Binding Specificity: AA 69-194

Purpose: Mouse anti-Human Thrombomodulin Antibody / CD141 [Sodium Azide Free]

Specificity: Cell surface, cytoplasmic

Purification: Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this Thrombomodulin antibody.

Immunogen: Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this Thrombomodulin antibody.

Application Details

Application Notes: FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 0.5-1 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 min at RT,ELISA: 2-4 μg/mL, order the BSA-free formulation for coating

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Thrombomodulin

Target: Thrombomodulin (THBD)

Alternative Name: Thrombomodulin

Background:

Target Description: It recognizes a protein of 75 kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.

Gene Symbol: THBD///THRM

Gene ID: 7056

UniProt: P07204