Pyruvate Kinase antibody (C-Term)

Catalog No. ABIN6294981

This anti-Pyruvate Kinase antibody is a Rabbit Polyclonal antibody detecting Pyruvate Kinase in . Suitable for Human, Mouse, Rat and Monkey.

Quick Overview for Pyruvate Kinase antibody (C-Term) (ABIN6294981)

Target: Pyruvate Kinase (PK)

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pyruvate Kinase antibody is un-conjugated

Application: Please inquire

Product Details anti-Pyruvate Kinase Antibody

Binding Specificity: AA 476-505, C-Term

Purpose: Rabbit Anti-Pyruvate Kinase (PKM2) (C-term) Antibody

Immunogen: This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2).

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Pyruvate Kinase

Target: Pyruvate Kinase (PK)

Alternative Name: Pyruvate Kinase

Background:

Target Description: There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

Gene Symbol: PKM

Gene ID: 5315

UniProt: P14618