FOXP2 antibody (C-Term)
Quick Overview for FOXP2 antibody (C-Term) (ABIN6295056)
Target
See all FOXP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 657-684, C-Term
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Purpose
- Rabbit Anti-FOXP2 (C-term) Antibody
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Immunogen
- This FOXP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-684 amino acids from the C-terminal region of human FOXP2.
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Restrictions
- For Research Use only
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- FOXP2 (Forkhead Box P2 (FOXP2))
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Alternative Name
- FOXP2
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Background
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Target Description: FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.
Gene Symbol: FOXP2
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Gene ID
- 93986
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UniProt
- O15409
Target
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