PGK1 antibody (Center)

Catalog No. ABIN6295138

This Rabbit Polyclonal antibody specifically detects PGK1 in . It exhibits reactivity toward Human and Mouse.

Quick Overview for PGK1 antibody (Center) (ABIN6295138)

Target: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGK1 antibody is un-conjugated

Application: Please inquire

Product Details anti-PGK1 Antibody

Binding Specificity: AA 117-145, Center

Purpose: Rabbit Anti-PGK1 (Center) Antibody

Immunogen: This PGK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the Central region of human PGK1.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for PGK1

Target: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Alternative Name: PGK1

Background:

Target Description: Also known as ATP:3-phosphoglycerate 1-phosphotransferase (EC 2.7.2.3), this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. New blood vessel formation or angiogenesis is critical for tumor expansion and metastasis. Lay et al. (2000) showed that the plasmin reductase isolated from conditioned medium of fibrosarcoma cells is the glycolytic enzyme phosphoglycerate kinase. They concluded that phosphoglycerate kinase not only functions in glycolysis but is secreted by tumor cells and participates in the angiogenic process as a disulfide reductase.

Gene Symbol: PGK1

Gene ID: 5230

UniProt: P00558

Pathways: Cellular Glucan Metabolic Process