ANGPTL4 antibody (Center)

Catalog No. ABIN6295169

The Rabbit Polyclonal anti-ANGPTL4 antibody has been validated for . It is suitable to detect ANGPTL4 in samples from Human and Mouse.

Quick Overview for ANGPTL4 antibody (Center) (ABIN6295169)

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL4 antibody is un-conjugated

Application: Please inquire

Product Details anti-ANGPTL4 Antibody

Binding Specificity: AA 138-167, Center

Purpose: Rabbit Anti-ANGPTL4 (Center) Antibody

Immunogen: This ANGPTL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the Central region of human ANGPTL4.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Alternative Name: ANGPTL4

Background:

Target Description: ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes.

Gene Symbol: ANGPTL4

Gene ID: 51129

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha