ISL1 antibody (Center)

Catalog No. ABIN6295190

The Rabbit Polyclonal anti-ISL1 antibody has been validated for . It is suitable to detect ISL1 in samples from Human and Mouse.

Quick Overview for ISL1 antibody (Center) (ABIN6295190)

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ISL1 antibody is un-conjugated

Application: Please inquire

Product Details anti-ISL1 Antibody

Binding Specificity: AA 156-185, Center

Purpose: Rabbit Anti-ISL1 (Center) Antibody

Immunogen: This ISL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ISL1.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for ISL1

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Alternative Name: ISL1

Background:

Target Description: ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Gene Symbol: ISL1

Gene ID: 3670

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding