AIRE antibody (Center)

Catalog No. ABIN6295388

The Rabbit Polyclonal anti-AIRE antibody has been validated for . It is suitable to detect AIRE in samples from Human and Mouse.

Quick Overview for AIRE antibody (Center) (ABIN6295388)

Target: AIRE (Autoimmune Regulator (AIRE))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIRE antibody is un-conjugated

Application: Please inquire

Product Details anti-AIRE Antibody

Binding Specificity: AA 64-92, Center

Purpose: Rabbit Anti-AIRE (Center) Antibody

Immunogen: This AIRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for AIRE

Target: AIRE (Autoimmune Regulator (AIRE))

Alternative Name: AIRE

Background:

Target Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).

Gene Symbol: AIRE

Gene ID: 326

UniProt: O43918

Pathways: Chromatin Binding