POMC antibody (N-Term)

Catalog No. ABIN6295490

The Mouse Monoclonal anti-POMC antibody has been validated for IHC, FACS and IF. It is suitable to detect POMC in samples from Human, Mouse and Rat.

Quick Overview for POMC antibody (N-Term) (ABIN6295490)

Target: POMC (Proopiomelanocortin (POMC))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This POMC antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-POMC Antibody

Binding Specificity: N-Term

Purpose: Mouse anti-Human/Mouse/Rat POMC Antibody [Sodium Azide Free]

Specificity: Cytoplasm

Purification: An N-terminal peptide from the ACTH region of human POMC was used as the immunogen for this POMC antibody.

Immunogen: An N-terminal peptide from the ACTH region of human POMC was used as the immunogen for this POMC antibody.

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for POMC

Target: POMC (Proopiomelanocortin (POMC))

Alternative Name: Pro-opiomelanocortin , Beta-endorphin, Met-enkephalin]

Background:

Target Description: POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin.

Gene Symbol: POMC

Gene ID: 5443

UniProt: P01189

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour