USP14 antibody (N-Term)

Catalog No. ABIN6295499

The Mouse Monoclonal anti-USP14 antibody has been validated for . It is suitable to detect USP14 in samples from Human, Mouse and Rat.

Quick Overview for USP14 antibody (N-Term) (ABIN6295499)

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This USP14 antibody is un-conjugated

Application: Please inquire

Product Details anti-USP14 Antibody

Binding Specificity: N-Term

Purpose: Mouse Anti-USP14 (N-term) Antibody

Immunogen: Purified His-tagged USP14 protein was used to produced this monoclonal antibody.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for USP14

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Alternative Name: USP14

Background:

Target Description: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

Gene Symbol: USP14

Gene ID: 9097

UniProt: P54578