Cytokeratin 5 antibody

Catalog No. ABIN6296027

The Mouse Monoclonal anti-Cytokeratin 5 antibody has been validated for IHC. It is suitable to detect Cytokeratin 5 in samples from Human, Mouse, Rat, Cow, Pig, Monkey, Guinea Pig, Goat and Frog.

Quick Overview for Cytokeratin 5 antibody (ABIN6296027)

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reactivity: Human, Mouse, Rat, Cow, Pig, Monkey, Guinea Pig, Goat, Frog

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 5 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Cytokeratin 5 Antibody

Purpose: Mouse anti-Human/Monkey/Cow/Pig/Goat/Rat/Mouse/Guinea Pig/Frog Multi Cytokeratin Antibody [IHC only]

Specificity: Cytoplasmic

Purification: A Keratin-enriched preparation from cultured human epithelial cells was used as the immunogen for the Multi Cytokeratin antibody.

Immunogen: A Keratin-enriched preparation from cultured human epithelial cells was used as the immunogen for the Multi Cytokeratin antibody.

Application Details

Application Notes: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Alternative Name: Keratin, type II cytoskeletal 5

Background:

Target Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This mAb recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8), 56.5 kDa (CK10), 53 kDa (CK13) and 45 kDa (CK18). This is a broad-spectrum mAb which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Gene Symbol: KRT5///KRT6A///K6A///KRT6D///KRT8///CYK8///KRT10///KPP///KRT13///KRT18///CYK18///PIG46

UniProt: P13647, P02538, P05787, P13645, P13646, P05783