ABO antibody

Catalog No. ABIN6296038

This Mouse Monoclonal antibody specifically detects ABO in IHC, IF, AGG, H and Func. It exhibits reactivity toward Human.

Quick Overview for ABO antibody (ABIN6296038)

Target: ABO (Histo-blood group A transferase (ABO))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ABO antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Agglutination (AGG), Haemagglutination (H), Functional Studies (Func)

Product Details anti-ABO Antibody

Purpose: Mouse anti-Human ABO Antibody (Blood Group Antigen A) [Sodium Azide Free]

Specificity: Cell surface

Purification: A mixture of erythrocytes of blood group A and glycoprotein fraction isolated from the saliva of secretors with blood group A was used as the immunogen for the ABO antibody.

Immunogen: A mixture of erythrocytes of blood group A and glycoprotein fraction isolated from the saliva of secretors with blood group A was used as the immunogen for the ABO antibody.

Application Details

Application Notes: Functional Activity-Erythrocyte Agglutination
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for ABO

Target: ABO (Histo-blood group A transferase (ABO))

Alternative Name: Histo-blood group ABO system transferase

Background:

Target Description: This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Gene Symbol: ABO

Gene ID: 28

UniProt: P16442