ABO antibody (N-Term)

Catalog No. ABIN1882200

Product Details anti-ABO Antibody

Target: ABO (Histo-blood group A transferase (ABO))

Binding Specificity: AA 41-68, N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ABO antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This ABO antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human ABO.

Clone: 593CT3-2-2

Isotype: IgM

Application Details

Application Notes: WB: 1:200~6400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ABO antibody (ABIN1882200)

Thuresson, Chester, Storry, Olsson et al.: "ABO transcript levels in peripheral blood and erythropoietic culture show different allele-related patterns independent of the CBF/NF-Y enhancer motif and multiple novel allele-specific variations in..." in: Transfusion, Vol. 48, Issue 3, pp. 493-504, (2008) (PubMed).

Vasan, Schlesinger, Arrode: "T cell immune responses to HIV-1." in: Frontiers in bioscience : a journal and virtual library, Vol. 12, pp. 2330-43, (2006) (PubMed).

Twu, Hsieh, Yu: "Expression of the histo-blood group B gene predominates in AB-genotype cells." in: Transfusion, Vol. 46, Issue 11, pp. 1988-96, (2006) (PubMed).

Jenkins, ODonnell: "ABO blood group determines plasma von Willebrand factor levels: a biologic function after all?" in: Transfusion, Vol. 46, Issue 10, pp. 1836-44, (2006) (PubMed).

Roubinet, Despiau, Calafell, Jin, Bertranpetit, Saitou, Blancher, Bertanpetit: "Evolution of the O alleles of the human ABO blood group gene." in: Transfusion, Vol. 44, Issue 5, pp. 707-15, (2004) (PubMed).

Target Details for ABO

Target: ABO (Histo-blood group A transferase (ABO))

Alternative Name: ABO (ABO Products)

Synonyms: A3GALNT antibody, A3GALT1 antibody, GTB antibody, NAGAT antibody, ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase antibody, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase) antibody, ABO antibody, Abo antibody

Background: This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.

Molecular Weight: 40934

NCBI Accession: NP_065202

UniProt: P16442