CTNNB1 antibody
Quick Overview for CTNNB1 antibody (ABIN6296226)
Target
See all CTNNB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Mouse anti-Human/Cow/Dog/Chicken Beta Catenin Antibody [Sodium Azide Free]
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Specificity
- Cell surface, cytoplasmic, cell junctions
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Purification
- Chicken b-Catenin was used as the immunogen for the b-Catenin antibody.
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Immunogen
- Chicken b-Catenin was used as the immunogen for the b-Catenin antibody.
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Application Notes
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Immunofluorescence: 1-2 μg/mL
WB: 1-2 μg/mL -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
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Alternative Name
- Catenin beta-1
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Background
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Target Description: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]
Gene Symbol: CTNNB1///CTNNB///OK///SW-cl.35///PRO2286
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Gene ID
- 1499
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UniProt
- P35222
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Pathways
- WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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