CD57 antibody

Catalog No. ABIN6296495

The Mouse Monoclonal anti-CD57 antibody has been validated for IHC and IF. It is suitable to detect CD57 in samples from Human.

Quick Overview for CD57 antibody (ABIN6296495)

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD57 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CD57 Antibody

Purpose: Mouse anti-Human CD57 Antibody [Sodium Azide Free]

Specificity: Cell surface, cytoplasmic

Purification: Human peripheral blood mononuclear cells were used as the immunogen for the anti-CD57 antibody.

Immunogen: Human peripheral blood mononuclear cells were used as the immunogen for the anti-CD57 antibody.

Application Details

Application Notes: Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD57

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Alternative Name: Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

Background:

Target Description: Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.

Gene Symbol: B3GAT1///GLCATP

Gene ID: 27087

UniProt: Q9P2W7

Pathways: Glycosaminoglycan Metabolic Process