Cadherin-16 antibody

Catalog No. ABIN6297292

This Mouse Monoclonal antibody specifically detects Cadherin-16 in IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Cadherin-16 antibody (ABIN6297292)

Target: Cadherin-16 (CDH16)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Cadherin-16 Antibody

Purpose: Mouse anti-Human/Mouse/Rat Cadherin 16 Antibody [IHC only]

Specificity: Cell surface with some cytoplasmic

Purification: Recombinant human protein was used as the immunogen for the Cadherin 16 antibody.

Immunogen: Recombinant human protein was used as the immunogen for the Cadherin 16 antibody.

Application Details

Application Notes: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: Cadherin-16

Background:

Target Description: Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Gene Symbol: CDH16///UNQ695///PRO1340

Gene ID: 1014

UniProt: O75309